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Laboratories are working under to pressure in the race to secure a vaccine against a possible winter pandemic (Photopress Kusano)

Swiss Pharmaceutical Companies Race for Vaccine


Roche and Novartis are heavily involved in the manufacture of vaccines to deal with the possible treat of Swine Flu.

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As the summer is moves along and the approach of winter brings with it the threat of a Swine Flu pandemic (Influenza Virus A, H1N1) in Europe, all eyes are on the Swiss pharmaceutical giants Roche and Novartis, in the hope of the arrival of a vaccine.

But the manufacture of this vaccine appears to be more difficult than first hoped.  Regarding the manufacture of a vaccine, a press spokesman for Novartis says that “the performance is weaker than anticipated. We'll have to produce for longer in order to achieve our objectives”.

150 Million Doses Annually

The Swiss pharmaceutical group has set itself the aim of producing 150 million doses per year. But this figure can not be confirmed until after the trials at the end of July, according to the spokesman, who announced a product for the European market in autumn.

Novartis reported “good progress in creating a vaccine against the new strain of influenza virus A (H1N1)”, claiming to have “started the production of this antigen on a large scale in all its plants in Europe”.  Novartis said “several orders of the H1N1 vaccine are being negotiated with more than 35 governments”, according to the laboratory. United States, France, Holland and Switzerland have placed them on order.

Roche, the other Swiss pharmaceutical giant which manufactures the only drug capable of fighting the virus containing the swine flu, Relenza, has benefited particularly from increased demand for Tamiflu.

Sales Triple

Sales of this drug have tripled to 1,000 million Swiss francs ($933 million 656 million Euros), with a particularly rapid rise in Japan (+1510%) and Europe (+869%). Roche plans to strengthen the production of Tamiflu, to achieve up to “the end of September, early October”, an annual production of 110 million treatments, reported a spokesman.

If necessary, the laboratory based in Basel, will put its 19 plants which are spread over a dozen countries at peak performance by the beginning of 2010, reaching an annual production of 400m treatments. By comparison, in the past five years, Roche produced 300 million treatments.

The Beginning of Clinical Trials

“Clinical trials have just started in some countries”, confirmed the World Health Organization (WHO), “we will know more in a few weeks after the first shots, because you have to see the reaction of people and their antibodies, to see if an injection is sufficient or if it takes two”, a spokesman for the organization said.

But in this particular race to produce vaccines, the Swiss pharmaceutical giants are not alone. British laboratory GlaxoSmithKline (GSK), which produces the above mentioned Relenza, has also begun developing a vaccine to combat a possible pandemic.

Swisslatin / adapted by Stephen Hinsch (6.8.2009)

 
 
 
 
 

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